Milwaukie High School's existence dates back as early as 1907. Originally constructed in 1925, the three-story building which houses the school today is one of the oldest buildings in the city of Milwaukie.
The school's first mascot, the Maroons, fell into disfavor with students because of its similarity to the word "moron." The student body voted on a new mascot as a result, and the Mustang was elected to replace the Maroons.
The Milwaukian, a school newspaper produced by students, was named the best high school newspaper in the nation in 2006], and the student publication was awarded the Quill and Scroll International First Place Award for newspaper excellence. Along with the newspaper, the school offers a variety of other media outlets for students, including the student yearbook, The Maroon, the video production program, Pulse Media, and the hands-on work experience in the technical field, MHS Tech Cadre.